by rss feed | Feb 11, 2026 | David Sinclair, ER-100, gene therapy, News Feeds, partial reprogramming, Reprogramming
The FDA has cleared a trial of ER-100 from Life Biosciences for eye rejuvenation. In the trial, ER-100 will deliver inducible expression of the three reprogramming factors. Oct-4, Sox-2, and Klf-4 are colloquially known together as OSK. This trial is an extension of...
by rss feed | Jul 27, 2025 | gene therapy, News Feeds, Sarepta, weekly reads
What is the deal with Sarepta lately? Things are spiraling. Before we dig into that, let’s give a RIP to Ozzy Osbourne, who had struggled with health issues. He was one of dozens of celebs to turn to unproven stem cells. Also, a heads up that student and stem...
by rss feed | Dec 8, 2022 | gene therapy, Haruko Obokata, He Jiankui, Hwang Woo-Suk, James Wilson, misconduct, News Feeds
There have been rare instances like with scientist James Wilson where researchers were involved in what I would call major misconduct but somehow managed to bounce back. In a sense, they were given second chances in part by regulators but also by other scientists or...
by rss feed | Feb 16, 2021 | biotechs, Bluebird Bio, gene therapy, News Feeds, Sickle Cell Disease
Recently I was going through a list I’m updating of regenerative medicine biotech companies including Bluebird Bio. Now just a few days later the world seems turned upside down for the firm and maybe to some degree for other companies doing related work....
by rss feed | Jan 10, 2021 | base-editing, gene editing, gene therapy, News Feeds, progeria, weekly reads
The paper of the week reports using base-editing, a kind of gene-editing, to reverse mutations associated with rapid aging syndromes, generally called progeria, but there are a lot of other interesting pubs to recommend for reading this week. I go over it all in this...
by rss feed | Jan 10, 2021 | base-editing, gene editing, gene therapy, News Feeds, progeria, weekly reads
The paper of the week reports using base-editing, a kind of gene-editing, to reverse mutations associated with rapid aging syndromes, generally called progeria, but there are a lot of other interesting pubs to recommend for reading this week. I go over it all in this...
