by rss feed | Aug 19, 2026 | anti-aging, David Sinclair, News Feeds, Reprogramming
I’ve been debating whether to unfollow longevity enthusiasts David Sinclair and Bryan Johnson on X. I find their posts about various anti-aging efforts to be fascinating on one level but also very unsettling. For one thing, some posts seem close to medical...
by rss feed | Feb 11, 2026 | David Sinclair, ER-100, gene therapy, News Feeds, partial reprogramming, Reprogramming
The FDA has cleared a trial of ER-100 from Life Biosciences for eye rejuvenation. In the trial, ER-100 will deliver inducible expression of the three reprogramming factors. Oct-4, Sox-2, and Klf-4 are colloquially known together as OSK. This trial is an extension of...
by rss feed | Dec 10, 2024 | anti-aging, Charles Brenner, David Sinclair, Investigative, News Feeds
I’ve written before about concerns related to longevity research hype from Harvard professor David Sinclair. The media often eats up statements about longevity from Sinclair and a few other scientists in that space. There is also endless coverage of the latest...
by rss feed | Mar 10, 2024 | Altos Labs, anti-aging, David Sinclair, News Feeds, Pura Munoz-Canoves, weekly reads
Anti-aging might already be the big regenerative medicine story of 2024 and it’s only early March. Anti-aging hype going to the dogs? One of my 20 stem cell and regenerative medicine predictions for 2024 was that longevity would continue to make big news...
by rss feed | Jul 18, 2023 | Aging, David Sinclair, hype, News Feeds, OSK-mediated rejuvenation, Reviews
The work of Harvard professor David Sinclair presents a kind of puzzle as his published research is generally interesting and important, but at the same time, I believe that he hypes anti-aging science. In addition, he promotes unproven supplements and lifestyle...
by rss feed | Mar 19, 2023 | David Sinclair, David Sinclair longevity, MD Stem Cells, News Feeds, weekly reads
A team led by Harvard professor David Sinclair had a recent Cell paper on reprogramming to fight aging that I reviewed here on The Niche. I thought the paper was exciting and important. Note that in vivo reprogramming was first done more than a decade ago. Sinclair...
