Article on longevity & David Sinclair provides new insights but has issues

by rss feed | Aug 19, 2026 | anti-aging, David Sinclair, News Feeds, Reprogramming

I’ve been debating whether to unfollow longevity enthusiasts David Sinclair and Bryan Johnson on X. I find their posts about various anti-aging efforts to be fascinating on one level but also very unsettling. For one thing, some posts seem close to medical...

Did Altos Labs just reprogram itself to focus on AI? Peter Walter, Steve Horvath, & more departures

by rss feed | May 27, 2026 | Altos Labs, anti-aging, Longevity AI, News Feeds, Steve Horvath

I’ve been following Altos Labs since its inception. The institution has intriguing, ambitious goals. For that reason, it’s been interesting that in terms of news on Altos, things have been relatively quiet for the last 4+ years. Some big changes have...

Weekly reads: Sam Altman Retro Bio anti-aging, skin organoids, more FDA turmoil

by rss feed | Dec 7, 2025 | anti-aging, News Feeds, Retro Bio, weekly reads

It seems like some multibillionaires either want to live forever or make more money by investing in longevity firms, or both, and that rings true again with Sam Altman’s $100M-plus bet on Retro Bio. Before we get to that, I wanted to mention that Tracy Hoeg, a...

Weekly reads: aging clocks easily swayed, OPC1 SCI trial, seesaw as Prasad is back at FDA

by rss feed | Aug 10, 2025 | aging clocks, anti-aging, DNAmFitAge, Health Flexing, News Feeds, weekly reads

I find it frustrating when longevity influencers claim that aging clocks show they have substantially de-aged themselves. Often by years. A tweet might be: “I ate nothing tasty for a year (or I took this expensive supplement) and now aging clocks show I’m...

Savage AI poem on extreme longevity efforts

by rss feed | Jul 23, 2025 | anti-aging, News Feeds, SB000

Readers of The Niche know that I lean skeptical about many of the statements from some corners of the longevity or anti-aging field. The Niche has covered research about senolytics, questionable stem cell efforts at longevity (unproven stem cells, etc.), in vivo...

Some skepticism as Shift Bioscience reports secret purported rejuvenation gene SB000 in preprint

by rss feed | Jun 11, 2025 | anti-aging, journal club, News Feeds, rejuvenation gene, SB000, Shift Bioscience

What if there was a rejuvenation gene that made adult cells younger without turning them into potentially destructive embryonic, fetal, or tumor cells? It could be transformative for how we think about cellular aging and have many impacts on health. A new preprint...