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Some skepticism as Shift Bioscience reports secret purported rejuvenation gene SB000 in preprint

by rss feed | Jun 11, 2025 | anti-aging, journal club, News Feeds, rejuvenation gene, SB000, Shift Bioscience

What if there was a rejuvenation gene that made adult cells younger without turning them into potentially destructive embryonic, fetal, or tumor cells? It could be transformative for how we think about cellular aging and have many impacts on health. A new preprint...

Weekly reads: longevity news on Retro & Altos Labs, free Harvard stem cell course, cord blood

by rss feed | Jun 1, 2025 | anti-aging, Health Flexing, News Feeds, Retro Biosciences, senolytics, weekly reads

Longevity research is a growing part of the overall regenerative medicine field. Rewinding, when I first started blogging here on The Niche in 2010, longevity was more of a fringe field. In just 15 years, it has become a generally legit area, even if one often filled...

Weekly reads: Topol on longevity biz, Peter Marks out at FDA, timeless NIH grant advice

by rss feed | Mar 30, 2025 | anti-aging, Eric Topol, FDA, News Feeds, Peter Marks, weekly reads

Most of us want longevity, especially if our quality of life remains generally solid as we age. The combination of length and quality of life is sometimes called “healthspan.” How do we get the maximum health span? Easier said than done. Not all of the...

Weekly reads: Altos Labs aging supplements pub, destructive NIH cuts, FDA warning, HSCs

by rss feed | Feb 9, 2025 | Altos Labs, anti-aging, BioStem Life Sciences, News Feeds, Steve Horvath, weekly reads

When I think of so-called aging supplements, visions of snake oil dance in my head. Possible benefits of supplements more generally have mostly not held up to long-term research. Supplements have risks too and so do purported longevity supplements. These pills...

Perspectives as Charles Brenner challenges David Sinclair on longevity claims

by rss feed | Jan 7, 2025 | anti-aging, Charles Brenner, Charles Brenner David Sinclair, News Feeds, Science hype

Professor Charles Brenner of City of Hope does great research, but I also applaud his efforts against longevity hype. Recently, Brenner and James Timmons publicly questioned some of the work of Harvard Professor David Sinclair. It’s a notable case of academics...

Refreshing WSJ piece on longevity ‘guru’ David Sinclair

by rss feed | Dec 10, 2024 | anti-aging, Charles Brenner, David Sinclair, Investigative, News Feeds

I’ve written before about concerns related to longevity research hype from Harvard professor David Sinclair. The media often eats up statements about longevity from Sinclair and a few other scientists in that space. There is also endless coverage of the latest...
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