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What are CAR-T cells & are they regenerative medicine?

by rss feed | Jul 19, 2022 | CAR-T cells, News Feeds, REGENERATIVE MEDICINE

The first time I heard CAR-T cells referred to as a regenerative medicine it made me stop and think. Are CAR-T therapies really a type of regenerative medicine? Generally, CAR-T cells are a designer immune cell therapy. They work by killing cancer cells and...

Stem cell reads: regeneration, 8C, MYC, CRISPR babies

by rss feed | Feb 27, 2022 | News Feeds, REGENERATIVE MEDICINE, stem cell journal

Another busy week including on the grant writing treadmill or should I say Mobius strip, but I’m always on the lookout for new reading and this week a lot popped up on regeneration. Also, a paper on healing and scarring. I regularly write about stem cell...

Grading my 21 stem cell & regenerative medicine predictions for 2021

by rss feed | Dec 22, 2021 | News Feeds, REGENERATIVE MEDICINE

The world of stem cell research and regenerative medicine is unpredictable but it’s fun to be a part of it and try to do predictions. Each year in late December or early January I make prognostications for the coming year for stem cell research and regenerative...

Regenerative reads: 3 CRISPR babies, FDA warning, diabetes, pubs

by rss feed | Nov 28, 2021 | CRISPR babies, News Feeds, REGENERATIVE MEDICINE, stem cells for diabetes

If you celebrate the Thanksgiving holiday I hope you had a nice one and, right before it started a new article popped on the scene about the CRISPR babies. Before we discuss those three gene-edited people, who are now growing up into little kids, we hit a milestone on...

Human induced pluripotent stem cell‐derived macrophages ameliorate liver fibrosis

by rss feed | Aug 30, 2021 | News Feeds, REGENERATIVE MEDICINE

Human induced pluripotent stem cells (iPSCs) are efficiently differentiated into both M1 and M2 macrophages. These cells were used to treat liver fibrosis in an immunodeficient mouse model. This treatment led to improvement in the fibrosis as measured by several...

Hematopoietic stem cell‐derived functional osteoblasts exhibit therapeutic efficacy in a murine model of osteogenesis imperfecta

by rss feed | Jul 14, 2021 | News Feeds, REGENERATIVE MEDICINE

Transplantation (Tp) of hematopoietic stem cells (HSCs) in Osteogenesis imperfecta (OI) mice causes replacement of mutated osteoblasts with normal osteoblasts (derived from HSCs) that lay down normal collagen and result in clinical improvements. Abstract Currently,...
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