by rss feed | Dec 5, 2021 | CONCISE REVIEW, News Feeds
Bromodomain protein 4 (BRD4) mediated transcription elongation in complex gene regulatory network during different stages of stem cell transitions. BRD4 modulates gene expression by recruiting PTEF-b for successful RNA polymerase II pause release and transcriptional...
by rss feed | Dec 5, 2021 | CORRIGENDUM, News Feeds
STEM CELLS, Volume 39, Issue 12, Page E5-E5, December 2021. Read Original
by rss feed | Dec 5, 2021 | CONCISE REVIEW, News Feeds
Schematic diagram of stem-cell derived two-dimensional schizophrenia (SCZ) culture models (left column) vs three-dimensional (3D) SCZ brain organoid models (middle column) to engineer neural networks for translational medicine. SCZ patient cells are reprogrammed...
by rss feed | Dec 5, 2021 | COVER IMAGE, News Feeds
Skin biopsies harvested 7 days after depilation and stained with H&E reveal higher numbers of anagenic hair follicles in the AhR+/+ than in the AhR−/− mice, suggesting that AhR positively regulates the telogen-to-anagen phase transition and hair growth. See...
by rss feed | Dec 5, 2021 | EMBRYONIC STEM CELLS/INDUCED PLURIPOTENT STEM CELLS, News Feeds, Uncategorized
Reprogramming of normal fibroblasts to induced pluripotent stem cells is characterized by low efficiency due to the upregulation of tumor suppressors and reprogramming-induced senescence (RIS). Spy1 can be combined with classical pluripotency factors to override RIS...
