by rss feed | Dec 2, 2020 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
A brief workflow showed the main discoveries in the manuscript, for example, the expression specificity of long noncoding RNAs (lncRNAs) in demarcating subpopulations of mammary epithelium, lineage‐specific lncRNAs in regulating lineage commitment through cis‐ or...
by rss feed | Dec 2, 2020 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
Through an interrelation between TGF‐β1 and Wnt signaling, ligament‐fibroblastic differentiation of adult periodontal ligament stem cells (hPDLCs) can be induced. Phosphorylated Smad3 by TGF‐β1 interacts with the active β‐catenin and moves into nucleus, followed by...
by rss feed | Dec 2, 2020 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
Separase haploinsufficiency in murine hematopoietic stem cells (HSCs) promote hematopoietic regeneration in vivo without altering the cellular quiescence. Abstract Cohesin recently emerged as a new regulator of hematopoiesis and leukemia. In addition to cohesin,...
by rss feed | Nov 25, 2020 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
Schematic representation of Angiomotin (AMOT) function during differentiation of trophoblast stem cells (TSCs). AMOT is expressed by ectoplacental cone on E7.5 during mouse placental development. Ectoplacental cone (EPC) harbors TSC niche. Low levels of AMOT in TSCs...
by rss feed | Nov 12, 2020 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
Model of SALL1 functions in odontoblastic differentiation. During odontoblastic differentiation, SALL1 binds to the regulatory element of Runx2 or interacts with RUNX2 to form a complex to regulate the odontoblastic cell fate of mDPCs at the early stage. In addition,...
by rss feed | Nov 9, 2020 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
Human umbilical cord tissue mesenchymal stromal cells (hCT‐MSCs) suppress the activation of helper T cells by reprograming monocytes and macrophages. Monocytes and macrophages physically interact with hCT‐MSCs via low‐density lipoprotein receptor‐related protein 1....
