by rss feed | Jan 25, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
CXCL12 is secreted by cells of the lamina propria and activates the chemokine receptor CXCR4 in globose basal cells of the olfactory epithelium. Receptor activation promotes division of these stem cells, and thereby regulates the size of the stem cell pool. Absence of...
by rss feed | Jan 22, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
All renin‐angiotensin system (RAS) components required for bioactive angiotensin II (Ang II) ‐synthesis and ‐signaling (Ang II type 1 [AT1] receptors) are synthesized locally in the aorta‐gonad‐mesonephros region of the developing mouse embryo, supporting the...
by rss feed | Jan 22, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
All renin‐angiotensin system (RAS) components required for bioactive angiotensin II (Ang II) ‐synthesis and ‐signaling (Ang II type 1 [AT1] receptors) are synthesized locally in the aorta‐gonad‐mesonephros region of the developing mouse embryo, supporting the...
by rss feed | Jan 18, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
Graphical abstract of the mechanism that cartilage endplate (CEP) inflammation accelerated the progression of intervertebral disc degeneration (IVDD). Normal cartilage endplate stem cell (CESC)‐derived exosomes (N‐Exos) can more effectively inhibit nucleus pulposus...
by rss feed | Jan 16, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
Kappa opioid receptors (OPRK1) promotes the transcription of the stem‐loop miRNA, miR‐7a‐2, through an unknown mechanism. The precursor miR‐7a‐2 in turn generates mature miR‐7a‐5p through processing. The miR‐7a‐5p targets and inhibits Pax6, which facilitates the...
by rss feed | Jan 13, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
In long bones, osteochondral progenitor cells function during rapid bone growth while osteoadipogenic progenitors act during bone maintenance. We showed that mTert is expressed in an age‐dependent manner and marks growth‐associated osteochondral progenitor cells...
