by rss feed | Feb 2, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
PINCH‐1‐Notch2 interaction promotes smooth muscle differentiation in response to mechanical cues from extracellular matrix (ECM). The decision of mesenchymal stem cells to differentiate into smooth muscle cells is influenced by their mechanoenvironment. This study...
by rss feed | Feb 2, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
PINCH‐1‐Notch2 interaction promotes smooth muscle differentiation in response to mechanical cues from extracellular matrix (ECM). The decision of mesenchymal stem cells to differentiate into smooth muscle cells is influenced by their mechanoenvironment. This study...
by rss feed | Feb 2, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
The LaCL stem cell niche does not express miR‐200, which regulates Sox2 expression. Progenitor cells exiting the stem cell niche start expressing miR‐200 to promote differentiation and the specification of cell fates for mature tooth development. miR‐200 therefore...
by rss feed | Feb 2, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
The LaCL stem cell niche does not express miR‐200, which regulates Sox2 expression. Progenitor cells exiting the stem cell niche start expressing miR‐200 to promote differentiation and the specification of cell fates for mature tooth development. miR‐200 therefore...
by rss feed | Feb 2, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
Myelin basic protein (MBP) presented in the spinal cord niche, but not the brain niche, causes the release of an inhibitory factor that regulates neural precursor cell kinetics and oligodendrogenesis. Hence, regionally distinct niches along the neuraxis respond...
by rss feed | Jan 25, 2021 | News Feeds, TISSUE‐SPECIFIC STEM CELLS
CXCL12 is secreted by cells of the lamina propria and activates the chemokine receptor CXCR4 in globose basal cells of the olfactory epithelium. Receptor activation promotes division of these stem cells, and thereby regulates the size of the stem cell pool. Absence of...
