Weekly The Niche reads: lab-grown embryos & thymus, more

by | Dec 13, 2020 | artificial embryos, chromatin, H3.3, histone H1, histones cancer, Nature publication fees, News Feeds, REGENERATIVE MEDICINE, the Niche, Weekend Reads

Today’s The Niche recommended weekly reads post includes both primary papers and also a few media pieces. I’m especially interested in the first piece on making more complex embryo-like structures from ES cells. This is a long way from just making embryoid...

Weekly The Niche reads: lab-grown embryos & thymus, more

by | Dec 13, 2020 | artificial embryos, chromatin, H3.3, histone H1, histones cancer, Nature publication fees, News Feeds, REGENERATIVE MEDICINE, the Niche, Weekend Reads

Today’s The Niche recommended weekly reads post includes both primary papers and also a few media pieces. I’m especially interested in the first piece on making more complex embryo-like structures from ES cells. This is a long way from just making embryoid...

Fibulin 5, a human Wharton’s jelly‐derived mesenchymal stem cells‐secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin‐RAC1 signaling axis

by | Dec 2, 2020 | News Feeds, REGENERATIVE MEDICINE

The common pathological symptom of dysmyelinating and demyelinating diseases is uncompact myelin ensheathments of the axons. Our findings suggest that FBLN5 binds to the Integrin receptors and promotes actin remodeling through RAC1 activation in the Schwann cells....

Adipose stem cell secretome markedly improves rodent heart and human induced pluripotent stem cell‐derived cardiomyocyte recovery from cardioplegic transport solution exposure

by | Nov 7, 2020 | News Feeds, REGENERATIVE MEDICINE

The damaging effects of University of Wisconsin (UW) solution are ameliorated by the inclusion of adipose‐derived stem/stromal cell secretome (ASC‐S). Mouse hearts stored in UW supplemented with ASC‐S demonstrated increased survivability ex vivo. This same phenomenon...