by rss feed | Nov 5, 2020 | EMBRYONIC STEM CELLS/INDUCED PLURIPOTENT STEM CELLS, News Feeds
Extensive cellular heterogeneity exists in cultures undergoing Yamanaka reprogramming. The ability to identify reprogramming progressive cells has practical and mechanistic implications. We report that reprogramming progressive cells can be conveniently identified by...
by rss feed | Oct 12, 2020 | EMBRYONIC STEM CELLS/INDUCED PLURIPOTENT STEM CELLS, News Feeds
This study demonstrated that brequinar (BRQ), an inhibitor for dihydroorotate dehydrogenase (DHODH), not only induced cell cycle arrest and cell death in mouse pluripotent stem cells (mPSCs) in vitro but also prevented tumorigenesis by selectively eliminating mPSCs in...
