by rss feed | Dec 2, 2020 | CONCISE REVIEW, News Feeds
Skin stem cells express a variety of G‐protein coupled receptors (GPCRs). GPCRs in the skin control multiple intracellular signaling cascades that ultimately regulate the balance of proliferation and differentiation in the stem cell compartment and the interactions of...
by rss feed | Dec 2, 2020 | CONCISE REVIEW, News Feeds
Skin stem cells express a variety of G‐protein coupled receptors (GPCRs). GPCRs in the skin control multiple intracellular signaling cascades that ultimately regulate the balance of proliferation and differentiation in the stem cell compartment and the interactions of...
by rss feed | Dec 2, 2020 | CONCISE REVIEW, News Feeds
TERC 3′ end maturation. Nascent TERC transcripts contain genomically encoded 3′ extensions (green). The extensions can be substrates for adenylation by PAPD5, which stimulates destruction of TERC by the RNA exosome. Conversely, PARN, TOE1, and possibly other...
by rss feed | Nov 25, 2020 | CONCISE REVIEW, News Feeds
An overview of the iterative process needed to address current biological and clinical challenges in order to improve reliability of future cell therapy trials in Huntington's disease. Abstract Huntington's disease (HD) is a rare inherited neurodegenerative disease...
by rss feed | Nov 19, 2020 | CONCISE REVIEW, News Feeds
The WNT, NF‐κB, and cholesterol biosynthesis pathways are essential signaling pathways for the tumor‐initiating ability, therapy resistance, and tumor progression of triple‐negative breast cancer stem cells. Abstract Since the discovery of breast cancer stem cells...
by rss feed | Nov 4, 2020 | CONCISE REVIEW, News Feeds
Neural crest stem cells possess exceptionally high stem cell potential post‐gastrulation. These cells give rise to a diverse range of derivatives of ectodermal, mesodermal‐like, and endodermal‐like origin, either directly from the initial embryonic neural crest cells...
