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Increased lipogenesis is critical for self‐renewal and growth of breast cancer stem cells: Impact of omega‐3 fatty acids

by rss feed | Dec 5, 2021 | cancer stem cells, News Feeds

Breast cancer stem cells (BCSC) have a distinct fatty acid profile due to the aberrant expressions of lipogenic enzymes (eg, FAS, SCD1, and FADS1/2), which are highly involved in sustaining their self-renewal, and proliferative capabilities. Omega-3 polyunsaturated...

Weekly reads: court case, cancer stem cells, skin, pluripotency, & more

by rss feed | May 16, 2021 | cancer stem cells, News Feeds, pluripotent stem cells, weekly reads

This was a busy week for me working on a grant due Friday and a bunch of other stuff including happily analyzing a bunch of data, but there were tons of interesting papers recently including on pluripotency. California stem cell clinic court case on in the background...

Cancer stem cell‐targeted therapeutic approaches for overcoming trastuzumabresistance in HER2‐positive breast cancer

by rss feed | Apr 9, 2021 | cancer stem cells, News Feeds

Several reported targeted therapies against breast cancer stem cells (BCSCs) to overcome trastuzumab resistance in HER2‐positive breast cancer. Abstract Application of the anti‐HER2 drug trastuzumab has significantly improved the prognosis of patients with the...

Activation of estrogen receptor beta signaling reduces stemness of glioma stem cells

by rss feed | Jan 20, 2021 | cancer stem cells, News Feeds

This study results suggest that estrogen receptor beta (ERβ) activation could be a promising therapeutic strategy to eradicate glioma stem cells (GSCs). ERβ knockout in glioblastoma cells increased GSCs, while ERβ overexpression resulted in loss of GSCs....

What is a teratoma? Research, prevention & treatment

by rss feed | Jan 14, 2021 | cancer stem cells, News Feeds, teratoma

Sometimes on The Niche or while teaching students as a professor here at UC Davis School of Medicine, I’ve been asked: What is a teratoma? Not all tumors are created equal and some like teratomas are particularly unusual. Exactly what is a teratoma? Teratomas...

What is a teratoma? Research & treatment

by rss feed | Jan 14, 2021 | cancer stem cells, News Feeds, teratoma

Sometimes on The Niche or while teaching students as a professor here at UC Davis School of Medicine, I’ve been asked: What is a teratoma? Not all tumors are created equal and some like teratomas are particularly unusual. Exactly what is a teratoma? Teratomas...
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