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Weekly reads: ER-100 trial update, ND AG stem cell alert, autoimmune CAR-T hurdles, AI effects on biologists, No on Prop 38

by rss feed | Oct 31, 2026 | Aspen Neuroscience, ER-100 trial, News Feeds, weekly reads

David Sinclair’s firm Life Biosciences recently launched a first-of-its-kind in vivo reprogramming trial called ER-100. I wrote about how the odds were against this trial succeeding but hoped I was wrong to be skeptical. The idea is to use a pulse of OCT4, SOX2,...

Bone-on-Bone Shoulder Arthritis: PRP, Stem Cells, and Shoulder Replacement

by rss feed | Oct 31, 2026 | News Feeds, Shoulder Pain

Marc Darrow, MD, JD When someone tells me, “My shoulder is bone-on-bone,” I want to know what that means in that person’s life. Is the pain keeping you awake? Can you put on a shirt, wash your hair, or reach a shelf? Have you stopped playing golf, or are you having...

New strategy identified for overcoming resistance to KRAS-targeted cancer therapies

by rss feed | Oct 31, 2026 | News Feeds

Researchers at Roswell Park Comprehensive Cancer Center have identified a promising strategy for overcoming one of the biggest challenges facing KRAS-targeted cancer therapies: treatment resistance. Read Original...

$4 million NIH grant advances AI-guided heart failure treatment

by rss feed | Oct 31, 2026 | News Feeds

A $4 million grant from the National Institutes of Health is helping faculty researchers in the University of Virginia School of Engineering and Applied Science develop an artificial intelligence tool to personalize treatments for people with heart failure. Read...

New project explores treatments to protect the brain from alphavirus infections

by rss feed | Oct 31, 2026 | News Feeds

A breakthrough in the fight against mosquito-borne viruses could one day help protect patients from devastating neurological complications. Read Original...

Reducing opioid medication during pregnancy may not ease neonatal opioid withdrawal syndrome

by rss feed | Oct 31, 2026 | News Feeds

Pregnant patients receiving medication to treat opioid use disorder should not reduce their medication dose out of fear that it will worsen withdrawal symptoms in their newborns, according to a new study led by researchers at the University of Maryland School of...
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