From 1908 when their existence was first hypothesized and the name “Stem Cell” was coined, it was then 70 years before definitive proof of their existence was shown in 1978. In the decades since then, research employing Stem Cells as treatments and therapies has exploded off the charts with research being conducted on nearly all the continents. The staff at is dedicated to combing the internet, trade journals, and medical publications to bring consumers the latest information and news about this exciting and promising field.


The following are just some examples of the Worldwide Research Effort:


South Africa
In March 2012 scientists at South Africa’s Council for Scientific and Industrial Research (CSIR) set up a facility for biomedical stem cell technology. Its gene expression and biophysics group generated the first induced pluripotent stem cells (iPSCs) in Africa, the CSIR announced.


China holds unrestrictive policies in regard to embryonic stem cell research – one of the most unrestrictive in the world. With this atmosphere Chinese scientists who have been educated and been trained in the West have flocked back to set up stem cell research laboratories in their home country. Stem cell researchers in the West attest to the fact that stem cell research facilities and researchers in China are already world class.

In Bangalore, India, the Institute for Stem Cell Biology and Regenerative Medicine (inStem) has state-of-the-art research facilities. Research at inStem includes stem cell biology, looking into mechanism that control differentiation and renewal, and impact of stem cells on recovery from stroke. Also in India, the Chaitanya Stem Cell Centre gives information on neurology, kidney, liver and many untreatable diseases. It also pushes regenerative medicine..

The following report is derived from the editorial. “New horizon in stem cell research,” of The Japan Times, February 3,2014 issue. Dr. Haruko Obokata and her team have found that body cells taken from mice can be reprogrammed into stem cells by exposing them to low-PH acid liquids. This new way of reprogramming adult cells into pluripotent cells (embryonic stem cells) is called “stimulus-triggered acquisition of pluripotency” or STAP. The STAP method is easier than that used by Dr. Shinya Yamanaka of Kyoto University, co-recipient with Sir John Gurdon of the Nobel Prize in Physiology or Medicine in 2012. In 2006 Yamanaka produced embryonic stem cells out of mouse skin by introducing four genes as growth factors. The cells are called induced pluripotent stem cells (iPSC). Yamanaka and his team did the same on human skin cells in 2007. STAP cells can form placenta which iPSC cannot do. “It is hoped that more efforts will be made so that the discovery will lead to the advancement of regenerative medicine.”

South Korea
The Stem Cell Research Center (SCRC) is a government-funded organization that supports stem cell research.The SCRC acts is a funding agency with 52 projects throughout South Korea. A national network, the Korean Society for Stem Cell Research, has been set up to facilitate stem cell research. The Stem Cell Research Center is the biggest stem cell center supported by Ministry of Science and Technology. Several other centers are supported by ministries like the Ministry of Health and Welfare. Several non-government organizations support stem cell research.


Some stem cell research trials being conducted in Australia include…..

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  • Condition: Graft Versus Host Disease. Mesenchymal Stromal Cells for Acute Graft Versus Host Disease. The trial plans to enrol 66 patients by December 2015 and to be completed by December 2016.
  • Condition: Osteoarthritis. HiQCell Joint Registry in Patients with Osteoarthritis Following the HiQCell Procedure. The first patients underwent this procedure in July 2012.
  • Condition: Brain tumours. Gene Therapy and Chemotherapy for the Treatment of Childhood Brain Tumours. The trial commenced in July 2012.
  • Condition: Bone repair. Cranial Reconstruction Using Mesenchymal Stromal Cells and Resorbable Biomaterials. This trial is conducted at the Royal Perth Hospital in Western Australia from January 2013 to December 2015.
  • Condition: Leukaemia. Pilot Study of Partially Human Leucocyte Antigen-Mismatched Stem Cell Infusions after Chemotherapy for Acute Myeloid Leukaemia.
  • Condition: Osteoarthritis. The Osteoarthritis Stem Cell Advanced Research Study. This trial is conducted by the Rheumatology Department of the Royal North Shore Hospital St Leonards in New South Wales and Regeneus Pty Ltd. (Internet. March 10,2014)



Belgian medical researchers succeeded in repairing bones using stem cells from fatty tissue.

The Saint Luc university clinic hospital in Brussels has a team that “has treated 11 patients, eight of them children, with fractures or bone defects that their bodies could not repair….” This was reported by the university on January 14, 2014. The breakthrough technique of Saint Luc’s centre for tissue and cellular therapy consists in removing a “sugar cube sized piece of fatty tissue from the patient, a less invasive process than pushing a needle into the pelvis and with a stem cell concentration they say is some 500 times higher.”

“The national assembly of France has voted to a lift a ban on embryonic stem cell research, which could pave the way for crucial scientific developments.” (France lifts its ban on embyonic stem cell reserch by Rebecca Taylor | Paris, France | | 7/17/13)

I-Stem is the largest French laboratory for research and development devoted to embryonic origin obtained by reprogramming gene. It is a collaboration between Inserm – National Institute of Health and Medical Research – and AFM-Telethon – French Association against Myopathies.

Germany defines stem cell research as “the scientific study of embryonic, fetal, adult, as well as induced pluripotent stem cells of living organisms of all kinds. By definition, stem cells are cells that are not yet fully developed and therefore have the potential to differentiate into different cell types.” In the medical and biological fields findings in stem cell research are obtained and turned to benefit consumers. The ultimate goal is regenerating defective organs.

Spain has a comprehensive regulatory framework for stem cell research, consisting of laws and regulations on stem cell research. One partner in research is the Centre for Genomic Regulation. This is reported by “Regulation of stem cell research in Spain,” updated in August 2012.

United Kingdom
Stem cell researchers of the United Kingdom “fertilised (the) first animal and then human eggs outside the body; a discovery that led to the creation of embryos outside the body and the subsequent birth of the first ‘test-tube baby’ (in vitro fertilisation) in 1978.” (

A British researcher, Sir John Gurdon, opened the door for animal cloning with the reprogramming of frog egg nucleus. He is co-winner of Shinya Yamanaka of Nobel Prize in Medicine in 2012 for their stem cell research.

The UK had pioneered in setting up a stem cell bank. “Set up in 2002 and partly funded by the MRC, the bank reduces the requirement for surplus embryos for the development of stem cell lines by individual research groups” (Internet. March 10,2014).
Researchers will go into guided differentiation into desired adult cells like muscles of the heart.

The potential of stem cells in screening drugs will be looked into. This may reduce the need to go through animal testing.
The Research Councils and Technology Strategy Board have agreed to develop regenerative medicine.


In 1963, Canadian scientists James Till and Ernest McCulloch identified and named stem cells. Since then Canadians have been at the forefront of scientific research, according to CBC digital archives (Internet March 10,2014).

Dr. Andras Nagy and his colleagues at Toronto’s Mount Sinai Hospital developed a method of turning skin cell into stem cells.” The new reprogramming method replaces a process that until now was done using viruses and carried the risk of damaging cell DNA and causing cancer.”

Stem cell DNA are inserted into a skin cell and ”removed after the skin cell transforms into a stem cell.” The produced stem cells are safer; the use of embryonic stem cells is not needed. This was announced in 2009 (Internet. March 10, 2014)

United States

“US President Barack Obama has reversed some barriers to human embryonic stem cell research,” in March 2009. This reversed the ban by Pres. Bill Clinton in 1995 owing to the ethical controversy over the use of human embryonic stem cells, according to the editorial of the Nature Cell Biology in 2010. “On August 23, 2012, in a decision favorable to proponents of embryonic stem cell research, the U.S. Court of Appeals for the D.C. Circuit… (dismissed) a lawsuit that challenged the Obama administration’s expansion of federal funding for embryonic stem cell research” (Internet, March 10,2014).”…Much remains to be done to ensure that stem cell research flourishes in the US in the coming decades,” the editorial said.

With the advent of the use of induced pluripotent stem cells research in stem cell therapy has advanced. However, since this therapy is considered to fall under drugs by the Food and Drug Administration of the USA, it will take long before this therapy becomes available to US consumers.

stemcellresearch-central-americaCENTRAL AMERICA

The Stem Cell Institute “arose from the unmet need to provide stem cell therapies that have been shown by others to meet the bar of safety in Phase I trials, but are not yet widely available because efficacy has not been proven.” It was founded by Neil Riordan, Ph.D. who comes from an American biotechnology company. Since 2006 the Institute has treated over 1800 patients. Dr. Riordan is the inventor of a nutritional supplement for use in stem cell therapy – Stem-Kine. It increases the population of stem cells and endothelium progenitor cells (EPC) in the bone marrow. EPCs circulate the stem cells to home to damaged part of the body and promotes healing.

“We collaborate with doctors and scientists at major universities in the US, Canada, and Costa Rica; including the University of California, San Diego, University of Utah, University of Western Ontario, University of Florida, University of Massachusetts, and the University of Costa Rica. We are in the planning stages of performing clinical trials in collaboration with New York University and the University of Miami” according to the Stem Cell Institute (Internet. March 10,2014).


The Brazilian government has set up a national Review Board system to increase research activity and the prospect of treating chronic and degenerative diseases using cell therapy since 2010.

The Science and Technology Department of the Ministry of Health in collaboration with the National Research Council have funded more than 100 projects since 2005. Several groups constitute the Brazilian Cell Therapy Network to promote interaction among research laboratories. “Around US$50 million have been disbursed to the Network by the government between 2005 and 2010” (Internet. March 10,2014).

Global Stem Cell News

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Scientists use stem cells to identify underlying cellular defects that cause Angelman syndrome
April 25, 2017 | rss feed
Researchers at UConn Health used stem cells derived from patients with Angelman syndrome to identify the underlying cellular defects that cause the rare neurogenetic disorder, an important step in the ongoing search for potential treatments for... [read more]
Cover Image
April 25, 2017 | rss feed
Cover Art: Low dose radiation causes basal cell carcinoma (BCC) with full penetrance in Ptch1 heterozygous mice. Image shows BCC in the back skin of an epidermis-specific Ptch1 heterozygous mouse 1 year after receiving 50 mGy irradiation. See Revenco... [read more]
Reduced Erg Dosage Impairs Survival of Hematopoietic Stem and Progenitor Cells
April 24, 2017 | rss feed
ERG, an ETS family transcription factor frequently overexpressed in human leukemia, has been implicated as a key regulator of hematopoietic stem cells. However, how ERG controls normal hematopoiesis, particularly at the stem and progenitor cell level, and how it contributes to leukemogenesis remain... [read more]
Bre Enhances Osteoblastic Differentiation by Promoting the Mdm2-Mediated Degradation of p53
April 24, 2017 | rss feed
Bre is a conserved cellular protein expressed in various tissues. Its major function includes DNA damage repair and anti-apoptosis. Recent studies indicate that Bre is potentially involved in stem cell differentiation although pathophysiological significance along with the molecular mechanisms is... [read more]
Unacylated ghrelin enhances satellite cell function and relieves the dystrophic phenotype in Duchenne muscular dystrophy mdx model
April 24, 2017 | rss feed
Muscle regeneration depends on satellite cells, quiescent precursors that, in consequence of injury or in pathological states such as muscular dystrophies, activate, proliferate, and differentiate to repair the damaged tissue. A subset of satellite cells undergoes self-renewal, thus preserving the... [read more]
Tip110 Deletion Impaired Embryonic And Stem Cell Development Involving Down-Regulation Of Stem Cell Factors Nanog, Oct4 And Sox2
April 24, 2017 | rss feed
HIV-1 Tat-interacting protein of 110 kDa, Tip110, plays important roles in multiple biological processes. In this study, we aimed to characterize the function of Tip110 in embryonic development. Transgenic mice lacking expression of a functional Tip110 gene (Tip110-/-) died post-implantation, and... [read more]
UCLA research overturns paradigm about how axons grow during embryonic development
April 21, 2017 | rss feed
New research by scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA overturns a long-standing paradigm about how axons -- thread-like projections that connect cells in the nervous system -- grow during... [read more]
Researchers develop new approach to protect stem cell recipients from graft-versus-host disease
April 21, 2017 | rss feed
Stem cell transplants can save lives, for example in patients with leukemia. However, these treatments are not free of risks. One complication that may occur is graft-versus-host disease (GVHD), basically donor-derived immune cells attacking the recipient’s... [read more]
Research shows potential way to limit damage to the brain caused by seizure disorder
April 21, 2017 | rss feed
Tiny vesicles isolated from adult mesenchymal stem cells and administered intranasally can limit the damage to the brain of animal models caused by a seizure disorder called status epilepticus, according to research published this week in the... [read more]
New model may provide vital insights into life-saving treatment for CMV infection
April 21, 2017 | rss feed
At-risk patients, such as those with HIV or transplant recipients, could benefit from potentially life-saving study carried out by a University of Surrey led group of international... [read more]
Protein primes mouse stem cells to quickly repair injury, Stanford study finds
April 20, 2017 | rss feed
Like drag car racers revving their engines at the starting line, stem cells respond more quickly to injury when they've been previously primed with one dose of a single protein, according to... [read more]
Penn researchers pinpoint underlying cause of Best disease
April 20, 2017 | rss feed
Named for Friedrich Best, who characterized the disease in 1905, Best disease, also known as vitelliform macular dystrophy, affects children and young adults and can cause severe declines in central vision as patients... [read more]
Researchers develop ultrasensitive method to detect protein involved in autoimmune diseases
April 19, 2017 | rss feed
Researchers in France have developed a new method that will allow doctors to detect minute amounts of a protein called interferon-a in patient... [read more]
Researchers find new way to prevent graft-versus-host disease after stem cell transplants
April 18, 2017 | rss feed
Through experimental work, an international team of researchers led by City of Hope's Defu Zeng, professor of diabetes immunology and hematopoietic cell transplantation, believe they may have found a way to prevent graft-versus-host disease after stem... [read more]
MIT researchers develop new technique to make high-resolution images of tissues
April 18, 2017 | rss feed
MIT researchers have developed a way to make extremely high-resolution images of tissue samples, at a fraction of the cost of other techniques that offer similar... [read more]
Cell cultures in petri dishes open new doors to brain research
April 14, 2017 | rss feed
The most complex organ in humans is the brain. Due to its complexity and, of course, for ethical reasons, it is extremely difficult to do scientific experiments on it - ones that could help us to understand neurodegenerative diseases like Parkinson's,... [read more]
Researchers correct Duchenne muscular dystrophy using gene-editing alternative
April 13, 2017 | rss feed
Using the new gene-editing enzyme CRISPR-Cpf1, researchers at UT Southwestern Medical Center have successfully corrected Duchenne muscular dystrophy in human cells and mice in the... [read more]
New approach makes cells resistant to HIV
April 13, 2017 | rss feed
Scientists at The Scripps Research Institute (TSRI) have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the... [read more]
Brief Report: Robo1 Regulates the Migration of Human Subventricular Zone Neural Progenitor Cells during Development
April 13, 2017 | rss feed
Human neural progenitor cell (NPC) migration within the subventricular zone (SVZ) of the lateral ganglionic eminence is an active process throughout early brain development. The migration of human NPCs from the SVZ to the olfactory bulb during fetal stages resembles what occurs in adult rodents. As... [read more]
TSRI scientists find new way to make cell population resistant to HIV
April 12, 2017 | rss feed
Scientists at The Scripps Research Institute have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the... [read more]
Researchers uncover mechanism that leads to disorders in pancreatic development, infant diabetes
April 12, 2017 | rss feed
Researchers at the University of Helsinki, Finland, have uncovered a mechanism through which a mutation in the STAT3 gene leads to a disorder in the development of the pancreas and to infant... [read more]
New nanowire technology may serve as platform to screen drugs for neurological diseases
April 12, 2017 | rss feed
A team led by engineers at the University of California San Diego has developed nanowires that can record the electrical activity of neurons in fine... [read more]
Alpha-ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction
April 11, 2017 | rss feed
Increased concentrations of reactive oxygen species (ROS) originating from dysfunctional mitochondria contribute to diverse aging-related degenerative disorders. But so far little is known about the impact of distinct ROS on metabolism and fate of stromal precursor cells. We here demonstrate that... [read more]
Peptide acts as mediator for learning
April 11, 2017 | rss feed
The ability of the brain to respond and adapt to changes is scientifically called brain plasticity. This ability is the basis of all learning... [read more]
Time-lapse video reveals cells essential for ‘birth’ of blood stem cells
April 11, 2017 | rss feed
St. Jude Children's Research Hospital study examines origin of blood stem cells during development and offers clues for making "donor blood" in the laboratory for therapeutic... [read more]
Scientists use time-lapse video to identify cells that trigger blood stem cell development
April 11, 2017 | rss feed
Like private investigators on a stake out, St. Jude Children's Research Hospital scientists used patience and video surveillance-like tools to identify cells that trigger blood cell... [read more]
Salk Institute receives additional $3 million Glenn Foundation gift to continue aging research
April 11, 2017 | rss feed
The Salk Institute has received a $3 million gift from the Glenn Foundation for Medical Research for the second time in 4 years, enabling the Institute to continue investigating the biology of normal human aging and age-related... [read more]
New transgenic mouse could help monitor potential dangers of emerging influenza viruses
April 10, 2017 | rss feed
Researchers in Germany have developed a transgenic mouse that could help scientists identify new influenza virus strains with the potential to cause a global... [read more]
New research sheds light on movement of white blood cells to sites of infection
April 10, 2017 | rss feed
One of the mysteries of the living body is the movement of cells - not just in the blood, but through cellular and other... [read more]
Hematologist-oncologist to lead bone marrow transplantation program for treating blood-borne cancers
April 10, 2017 | rss feed
Hematologist-oncologist Ahmad Samer Al-Homsi MD, MBA, will lead a new bone marrow transplantation program at NYU Langone's Perlmutter Cancer Center for treating blood-borne cancers, including leukemia, lymphoma and multiple myeloma, and potentially... [read more]
Salk scientists expand ability of stem cells to regrow any tissue type
April 10, 2017 | rss feed
When scientists talk about laboratory stem cells being totipotent or pluripotent, they mean that the cells have the potential, like an embryo, to develop into any type of tissue in the... [read more]
Stem cell drug screen yields potential alternative to statins
April 10, 2017 | rss feed
Scientists at the Medical University of South Carolina (MUSC) have found that a class of heart failure drugs might decrease low-density lipoprotein (LDL) cholesterol levels in patients who do... [read more]
WSU researchers improve technology to save sperm stem cells
April 10, 2017 | rss feed
Washington State University researchers have found a promising way to preserve sperm stem cells so boys could undergo cancer treatment without risking their... [read more]
Concise review: Stem cells in Osteoimmunology
April 8, 2017 | rss feed
Bone remodeling is a lifelong process in which mature bone tissue is removed from the skeleton by bone resorption and is replenished by new during ossification or bone formation. The remodeling cycle requires both the differentiation and activation of two cell types with opposing functions. The... [read more]
Study identifies key mediator in learning process
April 7, 2017 | rss feed
The ability of the brain to respond and adapt to changes is scientifically called brain plasticity. This ability is the basis of all learning... [read more]
Researchers discover small protein essential for formation of skeletal muscle
April 7, 2017 | rss feed
UT Southwestern Medical Center researchers discovered a small protein named Myomixer essential for the formation of skeletal muscle – findings that could eventually help treat genetic diseases such as muscular dystrophy and other... [read more]
Researchers identify molecular switch that converts skin cells into blood vessel cells
April 7, 2017 | rss feed
Researchers from the University of Illinois at Chicago have identified a molecular switch that converts skin cells into cells that make up blood vessels, which could ultimately be used to repair damaged vessels in patients with heart disease or to... [read more]
Salk scientists discover chemical cocktail that enables stem cells to generate tissues
April 7, 2017 | rss feed
When scientists talk about laboratory stem cells being totipotent or pluripotent, they mean that the cells have the potential, like an embryo, to develop into any type of tissue in the... [read more]
Protocol violations in reduced radiotherapy lead to worse outcomes in children with brain tumors
April 6, 2017 | rss feed
A team of investigators has determined that young children participating in a clinical trial to assess the effectiveness of reduced radiotherapy did worse when there were deviations from the treatment... [read more]
Scientists develop new understanding of how first blood cells form during human development
April 6, 2017 | rss feed
Scientists at Lund University in Sweden have developed a new understanding of how the first blood cells form during human development as they transition from endothelial cells to form blood cells of different... [read more]
Treating heart failure with muscle stem cell patch
April 6, 2017 | rss feed
Treating heart failure using muscle stem cells taken from the patient may be a viable option. A new study demonstrates its safety in human... [read more]
New initiative to study relationship between brain and obesity
April 6, 2017 | rss feed
The Naomi Berrie Diabetes Center at Columbia University Medical Center has launched an initiative to study the relationship between the brain and metabolic disorders such as obesity and... [read more]
Researchers achieve new step towards treatment of myotubular myopathy using gene therapy
April 6, 2017 | rss feed
A team of researchers in France, led by Dr. Ana Buj-Bello (Genethon/Inserm) and teams at the University of Washington and Harvard Medical School in the United States, achieved a new step towards the treatment of myotubular myopathy by gene... [read more]
Eating potassium-rich foods could be key to lowering blood pressure
April 5, 2017 | rss feed
Eating potassium-rich foods like sweet potatoes, avocados, spinach, beans, bananas -; and even coffee -; could be key to lowering blood pressure, according to Alicia McDonough, PhD, professor of cell and neurobiology at the Keck School of Medicine of... [read more]
Adipogenic Differentiation of Mesenchymal Stem Cells Alters Their Immunomodulatory Properties in a Tissue-Specific Manner
April 4, 2017 | rss feed
Chronic inflammation is associated with formation of ectopic fat deposits that might represent damage-induced aberrant mesenchymal stem cell (MSC) differentiation. Such deposits are associated with increased levels of inflammatory infiltrate and poor prognosis. Here we tested the hypothesis that... [read more]
Researchers discover possible new route to regenerating function lost in diabetes
April 4, 2017 | rss feed
In people with type I diabetes, insulin-producing beta cells in the pancreas die and are not replaced. Without these cells, the body loses the ability to control blood... [read more]
Hypoxia-Mediated Epigenetic Regulation of Stemness in Brain Tumor Cells
April 4, 2017 | rss feed
Activation of pluripotency regulatory circuit is an important event in solid tumor progression and the hypoxic microenvironment is known to enhance the stemness feature of some cells. The distinct population of cancer stem cells (CSCs)/tumor initiating cells exist in a niche and augment invasion,... [read more]
Organoids in cell culture dish offer new insights into development of the brain
April 4, 2017 | rss feed
A new method could push research into developmental brain disorders an important step forward. This is shown by a recent study at the University of Bonn in which the researchers investigated the development of a rare congenital brain... [read more]
Mesenchymal Stem Cell Microvesicles Attenuate Acute Lung Injury in Mice Partly Mediated by Ang-1 mRNA
April 4, 2017 | rss feed
Microvesicles (MVs) derived from human mesenchymal stem cells (MSC MVs) were demonstrated to ameliorate inflammation in lungs. We have found their content of mRNA for keratinocyte growth factor was partly involved in their therapeutic effects. As MSC MVs also contained a substantial quantity of... [read more]
Hypoxia Inducible Factor-1α Potentiates Jagged 1-Mediated Angiogenesis by Mesenchymal Stem Cell-Derived Exosomes
April 4, 2017 | rss feed
Insufficient vessel growth associated with ischemia remains an unresolved issue in vascular medicine. Mesenchymal stem cells (MSCs) have been shown to promote angiogenesis via a mechanism that is potentiated by hypoxia. Overexpression of hypoxia inducible factor (HIF)-1α in MSCs improves their... [read more]
Researchers identify biomarker for likely aggressive, early-stage breast cancers
April 4, 2017 | rss feed
The one-size-fits-all approach to early stage breast cancer creates a paradox: Millions of dollars are spent on unnecessary surgeries and radiation to treat women with low-risk 'in situ' lesions, an estimated 85% of which would never progress to... [read more]
Essen BioScience Launches the IncuCyte® S3 Live-Cell Analysis Platform
April 3, 2017 | rss feed
Essen BioScience, a pioneer and leader in the field of cell-based assays and instrumentation used for drug discovery and basic research, has launched the IncuCyte® S3 live-cell analysis platform for real-time, automated measurements of cell health, proliferation, movement and function directly... [read more]
Origin and characterization of alpha smooth muscle actin-positive cells during murine lung development
April 3, 2017 | rss feed
ACTA2 expression identifies pulmonary airway and vascular smooth muscle cells (SMCs) as well as alveolar myofibroblasts (MYF). Mesenchymal progenitors expressing fibroblast growth factor 10 (Fgf10), Wilms tumor 1 (Wt1), or glioma-associated oncogene 1 (Gli1) contribute to SMC formation from early... [read more]
Intranuclear Actin Structure Modulates Mesenchymal Stem Cell Differentiation
April 3, 2017 | rss feed
Actin structure contributes to physiologic events within the nucleus to control mesenchymal stromal cell (MSC) differentiation. Continuous cytochalasin D (Cyto D) disruption of the MSC actin cytoskeleton leads to osteogenic or adipogenic differentiation, both requiring mass transfer of actin into... [read more]
Experts to present diverse advances in neuromodulation at INS congress
March 31, 2017 | rss feed
Experts will present diverse advances in neuromodulation from May 27 to June 1, 2017 at the 13th World Congress of the International Neuromodulation Society in Edinburgh,... [read more]
Researchers use stem cells to model different genetic scenarios that underlie neurologic disease
March 30, 2017 | rss feed
Researchers at Case Western Reserve University School of Medicine have successfully grown stem cells from children with a devastating neurological disease to help explain how different genetic backgrounds can cause common... [read more]
Researchers shed light on genome reorganization after fertilization in single-cell mammalian embryo
March 30, 2017 | rss feed
Using a newly developed method researchers at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences have been able to shed light on the complexity of genome reorganization occurring during the first hours after fertilization in... [read more]
New strategy identifies potential drugs and targets for brain repair
March 30, 2017 | rss feed
Researchers have discovered drugs that activate signaling pathways leading to specific adult brain cell types from stem cells in the mouse brain, according to a study published in the open... [read more]
Case Western Reserve University researchers turn urine into research tools
March 30, 2017 | rss feed
One of the biggest challenges in studying Down syndrome is finding the right research... [read more]
Scientists develop new tool to analyse single-cell RNA data in pre-malignant blood cancers
March 29, 2017 | rss feed
Wellcome Trust Sanger Institute scientists and their collaborators have developed a new analysis tool that was able to show, for the first time, which genes were expressed by individual cells in different genetic versions of a benign blood... [read more]
Research uncovers vast inequalities in cancer care for older patients with leukaemia
March 28, 2017 | rss feed
New research conducted by Leukaemia CARE into the lives of older people living with blood cancers has uncovered vast inequalities in cancer care for the elderly compared with younger... [read more]
Study shows potential of stem cell therapy to repair lung damage
March 28, 2017 | rss feed
A new study has found that stem cell therapy can reduce lung inflammation in an animal model of chronic obstructive pulmonary disease (COPD) and cystic... [read more]
New tools to study the origin of embryonic stem cells
March 27, 2017 | rss feed
Researchers at Karolinska Institutet have identified cell surface markers specific for the very earliest stem cells in the human... [read more]
Cover Image
March 27, 2017 | rss feed
Cover Art: Control embryoid bodies on day 6 exhibiting a wellstructured surface layer of extraembryonic endoderm. Left image shows expression of Gata6 (red). Right image depicts α-feto protein (AFP) expression (green). Nuclei were stained with DAPI... [read more]
Stem cell therapy can reduce lung inflammation in mouse model of COPD and cystic fibrosis
March 25, 2017 | rss feed
A new study has found that stem cell therapy can reduce lung inflammation in an animal model of chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Although, still at a pre-clinical stage, these findings have important potential... [read more]
Erectile dysfunction: Stem cell therapy restores sexual function in phase I trial
March 25, 2017 | rss feed
Early trial results reveal how stem cell therapy allowed men with erectile dysfunction to engage in sexual intercourse within 6 months of... [read more]
Random DNA copying ‘mistakes’ account for most cancer mutations, study finds
March 24, 2017 | rss feed
Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that cause... [read more]
Surprising new role for lungs: Making blood
March 24, 2017 | rss feed
Using video microscopy in the living mouse lung, UC San Francisco scientists have revealed that the lungs play a previously unrecognized role in blood... [read more]
OTUD6B gene mutations linked to physical and intellectual deficits
March 24, 2017 | rss feed
An international team of researchers from institutions around the world, including Baylor College of Medicine, has discovered that mutations of the OTUD6B gene result in a spectrum of physical and intellectual... [read more]
Scientists identify molecule that could be targeted to prevent vision loss in diabetics and preterm infants
March 23, 2017 | rss feed
Researchers at Bascom Palmer Eye Institute, part of the University of Miami Miller School of Medicine, have identified a new molecule that induces the formation of abnormal blood vessels in the eyes of diabetic... [read more]
Scientists identify molecule that could be targeted to prevent vision loss in diabetics and preterm infants
March 23, 2017 | rss feed
Researchers at Bascom Palmer Eye Institute, part of the University of Miami Miller School of Medicine, have identified a new molecule that induces the formation of abnormal blood vessels in the eyes of diabetic... [read more]
WPI researchers grow beating human heart cells on spinach leaves
March 23, 2017 | rss feed
Researchers face a fundamental challenge as they seek to scale up human tissue regeneration from small lab samples to full-size tissues, bones, even whole organs to implant in people to treat disease or traumatic injuries: how to establish a vascular... [read more]
Intrastriatal Transplantation of Human Neural Stem Cells Restores the Impaired Subventricular Zone in Parkinsonian Mice
March 22, 2017 | rss feed
Cell replacement therapy using neural stem cells (NSCs) transplantation has recently emerged as a promising method of Parkinson's disease (PD) treatment; however, the underlying mechanisms are not fully understood. To gain new insights into the mechanisms of 6-hydroxydopamine (6-OHDA)-induced... [read more]
Study shows stem cell therapy is safe for stroke patients
March 22, 2017 | rss feed
A multicenter trial looking at whether a single dose of millions of adult, bone-marrow-derived stem cells can aid stroke recovery indicates it's safe and well-tolerated by patients but may... [read more]
Parasitic fish offers unique insights into evolution of gut neurons in ancient vertebrates
March 21, 2017 | rss feed
Lamprey are slimy, parasitic eel-like fish, one of only two existing species of vertebrates that have no jaw. While many would be repulsed by these creatures, lamprey are exciting to biologists because they are so primitive, retaining many... [read more]
Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model
March 21, 2017 | rss feed
Using a new cellular model, innovative gene therapy approaches for the hereditary immunodeficiency Chronic Granulomatous Disease can be tested faster and cost-effectively in the lab for their... [read more]
Research findings hold promise to generate blood cell precursors from hPSCs
March 21, 2017 | rss feed
The Galat laboratory at Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, has developed an elegant system to derive blood cell precursors from human pluripotent stem cells... [read more]
Scientists use parsley and other plants to create human stem cell scaffolds
March 21, 2017 | rss feed
Borrowing from nature is an age-old theme in science. Form and function go hand-in-hand in the natural world and the structures created by plants and animals are only rarely improved on by... [read more]
Salk scientists develop new way to find responders to lithium therapy
March 21, 2017 | rss feed
For roughly one-third of people diagnosed with bipolar disorder, lithium is a miracle drug, effectively treating both their mania and depression. But once someone is diagnosed, it can take up to a year to learn whether that person will be among the 30... [read more]
Bioengineered tooth restoration in a large mammal
March 21, 2017 | rss feed
Researchers at Okayama University report in Scientific Reports successful tooth regeneration in a postnatal large-animal... [read more]
Scientists to examine how stem cells proliferate faster in microgravity without side effects
March 21, 2017 | rss feed
Growing significant numbers of human stem cells in a short time could lead to new treatments for stroke and other diseases. Scientists are sending stem cells to the International Space Station to test whether these cells proliferate faster in... [read more]
Early treatment with stem cells can safely help recovery in stroke patients, study shows
March 20, 2017 | rss feed
A multicenter trial looking at whether a single dose of millions of adult, bone-marrow-derived stem cells can aid stroke recovery indicates it's safe and well-tolerated by patients but may not significantly improve their recovery within the first... [read more]
Electroacupuncture releases stem cells to relieve pain, promote tissue repair, study finds
March 20, 2017 | rss feed
A study led by Indiana University School of Medicine researchers demonstrates how electroacupuncture triggers a neurological mechanism that can help promote tissue repair and relieve... [read more]
Concise Review: MSC Adhesion Cascade—Insights into Homing and Transendothelial Migration
March 18, 2017 | rss feed
Mesenchymal stem cells (MSCs) are promising candidates for adult cell therapies in regenerative medicine. To fully exert their potential, efficient homing and migration toward lesion sites play an important role. Local transplantation deposits MSC in spatial proximity to the lesion, but often... [read more]
Researchers use Syngene’s G:BOX Chemi XRQ image analysis system in cardiac research
March 17, 2017 | rss feed
Syngene, a world-leading manufacturer of image analysis solutions is delighted to announce that the G:BOX Chemi XRQ high resolution, multi-application image analysis system is being successfully used at the Lithuanian University of Health Sciences... [read more]
Unproven stem cell ‘therapy’ blinds three patients at Florida clinic
March 17, 2017 | rss feed
Three people with macular degeneration were blinded after undergoing an unproven stem cell treatment that was touted as a clinical trial in 2015 at a clinic in... [read more]
From skin to brain: Stem cells without genetic modification
March 17, 2017 | rss feed
A discovery, several years in the making, by a University at Buffalo research team has proven that adult skin cells can be converted into neural crest cells (a type of stem cell) without... [read more]
Electroacupuncture triggers neurological mechanism to promote tissue repair and relieve pain, study shows
March 17, 2017 | rss feed
A study led by Indiana University School of Medicine researchers demonstrates how electroacupuncture triggers a neurological mechanism that can help promote tissue repair and relieve injury-induced... [read more]
Study uncovers genetic link to aggressive form of prostate cancer
March 17, 2017 | rss feed
An international study published in the Journal of the National Cancer Institute has identified a genetic connection to the aggressive form of prostate... [read more]
Researchers create model of anorexia nervosa using stem cells
March 16, 2017 | rss feed
An international research team, led by scientists at University of California San Diego School of Medicine, has created the first cellular model of anorexia nervosa (AN), reprogramming... [read more]
Study identifies molecular clues for age-related intestinal issues
March 16, 2017 | rss feed
Intestinal stem cells rejuvenate daily so bowels will stay healthy and function normally, but a new study in Cell Reports suggests they also age along with people and lose their... [read more]
Electroacupuncture Promotes Central Nervous System-Dependent Release of Mesenchymal Stem Cells
March 16, 2017 | rss feed
Electroacupuncture (EA) performed in rats and humans using limb acupuncture sites, LI-4 and LI-11, and GV-14 and GV-20 (humans) and Bai-hui (rats) increased functional connectivity between the anterior hypothalamus and the amygdala and mobilized mesenchymal stem cells (MSCs) into the systemic... [read more]
UB research yields neural crest cells from adult skin cells without genetic modification
March 16, 2017 | rss feed
A discovery, several years in the making, by a University at Buffalo research team has proven that adult skin cells can be converted into neural crest cells (a type of stem cell) without any genetic modification, and that these stem cells can yield... [read more]
Antibody treats pediatric brain tumors safely and effectively in mice
March 16, 2017 | rss feed
Five types of pediatric brain cancer were safely and effectively treated in mice by an antibody that causes immune cells to engulf and eat tumors without hurting healthy brain cells, according to a new study by researchers at the Stanford University... [read more]
LCSB researchers identify how the body influences differentiation of progenitor cells
March 15, 2017 | rss feed
Stem cells are unspecialised cells that can develop into any type of cell in the human body. So far, however, scientists only partially understand how the body controls the fate of these all-rounders, and what factors decide whether a stem cell will... [read more]
Breakthrough brain repair discovery could revolutionise treatment of Multiple Sclerosis
March 15, 2017 | rss feed
Queen's University Belfast scientists have discovered that specific cells from the immune system are key players in brain repair - a fundamental breakthrough that could revolutionise the treatment of debilitating neurological disorders such as... [read more]
High Aldehyde Dehydrogenase Activity Identifies a Subset of Human Mesenchymal Stromal Cells with Vascular Regenerative Potential
March 15, 2017 | rss feed
During culture expansion, multipotent mesenchymal stromal cells (MSCs) differentially express aldehyde dehydrogenase (ALDH), an intracellular detoxification enzyme that protects long-lived cells against oxidative stress. Thus, MSC selection based on ALDH-activity may be used to reduce heterogeneity... [read more]