Many of the complex folded shapes that form mammalian tissues can be recreated with very simple instructions, UC San Francisco bioengineers report December 28 in the journal Developmental Cell.
Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells.
Cover Art: Preservation of human retinal ganglion cells after culture with human mesenchymal stem cells for 7 days in post mortem retinal explants. See Osborne et al. beginning on page 65.
The rodent model that received fat grafting in the setting of retained tumor was successfully developed. Grafts showed that injection of more cancer cells correlated with bigger tumor masses (A, E). Fat injection had a significant increasing effect on tumor and...